منابع مشابه
Photodynamic Action of Hypericin on Cyanobacteria, Synechocystis and Synechoccus (Anacystis nidulans)
Hypericin, Cyanobacteria, Photosynthesis, Photodynamic Action The photodynamic action of hypericin on photosynthesis and respiration were monitored in Synechocystis sp PCC 6803 and Synechoccus ATCC 6311 (Anacystis nidulans). An oxygen electrode was used to measure net oxygen evolution or consumption. The amount of hyperi cin required to inhibit photosynthesis was quantitively determined. Photo...
متن کاملHypericin-photodynamic therapy induces human umbilical vein endothelial cell apoptosis.
The conventional photosensitizers used in photodynamic therapy (PDT), such as haematoporphyrin (HP), have not yet reached satisfactory therapeutic effects on port-wine stains (PWSs), due largely to the long-term dark toxicity. Previously we have showed that hypericin exhibited potent photocytotoxic effects on Roman chicken cockscomb model of PWSs. However, the molecular mechanism of hypericin-m...
متن کاملPhotodynamic Therapy with Hypericin Improved by Targeting HSP90 Associated Proteins
In this study we have focused on the response of SKBR-3 cells to both single 17-DMAG treatment as well as its combination with photodynamic therapy with hypericin. Low concentrations of 17-DMAG without any effect on survival of SKBR-3 cells significantly reduced metabolic activity, viability and cell number when combined with photodynamic therapy with hypericin. Moreover, IC10 concentation of 1...
متن کاملSelective photodynamic inactivation of Staphylococcus aureus with Hypericin
Introduction: Staphylococcus aureus is a gram positive bacteria responsible by localized and systemic infections. The bacterial resistance to antibiotics is a huge problem and a challenge for the development of new therapeutic modalities [1]. The photodynamic inactivation of microorganisms (PDI) is a promising technique to fight localized infections based on a association of a photosensitizer (...
متن کاملHypericin in the Dark: Foe or Ally in Photodynamic Therapy?
Photosensitizers (PSs) in photodynamic therapy (PDT) are, in most cases, administered systemically with preferential accumulation in malignant tissues; however, exposure of non-malignant tissues to PS may also be clinically relevant, when PS molecules affect the pro-apoptotic cascade without illumination. Hypericin (Hyp) as PS and its derivatives have long been studied, regarding their photodyn...
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ژورنال
عنوان ژورنال: Photochemistry and Photobiology
سال: 1986
ISSN: 0031-8655,1751-1097
DOI: 10.1111/j.1751-1097.1986.tb05646.x